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KMID : 1041220130510020147
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Journal of Sericultural and Entomological Science
2013 Volume.51 No. 2 p.147 ~ p.152
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Comparison of fibrinolytic activity from Korean indigenous insects
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Kim Hyun-Ae
Lee Sang-Han
Choi Young-Cheol
Park Kwan-Ho
Hwang Jae-Sam
Kim Nam-Jung
Nam Sung-Hee
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Abstract
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The fibrinolytic activity of aqueous extracts from Korean indigenous insects were studied. Fibrinolytic activity of aqueous extract from 5 insects (larva and adult parts of Meloimorpha japonica, Allomyrina dichotoma, Cetonia pilifera, Apis mellifera) showed 2.7-fold potent than that of plasmin used as a positive control. In addition, the fibrinolytic activity was observed through the degradation products by SDS-PAGE. The extracts efficiently hydrolyzed α-, β- and γ chains of human fibrinogen. This study suggested that aqueous extracts from Korean indigenous insects have potential in developing a useful source of antithrombosis agent(s).
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KEYWORD
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Antithrombosis, Indigenous insects, Fibrinolytic activity
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